摘要目的 探讨胃十二指肠溃疡穿孔(perforated gastroduodenal ulcer,PGDU)非手术治疗的疗效和适应证范围.方法 回顾性分析2005年1月至2015年10月间在深圳市第四人民医院PGDU患者236例,以宽适应证选择非手术综合治疗,按临床标准评估疗效,治疗达标后通过早期胃镜检查确定穿孔病因.结果 本组236例PDGU患者中8例中转手术治疗(3.4％),非手术治愈228例(96.6％),并发症发生率6.8％,无1例并发感染性休克或死亡.在非手术治愈的病例中,治疗后住院同期接受胃镜检查213例(93.4％)确诊为胃十二指肠溃疡,未行胃镜检查确诊15例(6.6％).结论 非手术的综合治疗对多数无严重并发症的PGDU效果良好.

abstractsObjective To study the curative effect of non-operative treatment for perforated gastroduodenal ulcer (PGDU) and indications range.Methods Under broad indications PDGU patients underwent non-surgical treatment according to the standard of clinical evaluation curative effect,then perforation causes were determined by the early gastroscopy after curative effect is up to standards.Results From January 2005 to October 2015 PGDU was diagnosed in 236 cases and treated non-operatively.8 cases were converted to surgical treatment (3.4％).228 cases were cured (96.6％) non-surgically.Among those 213 cases (93.4％) underwent gastroscopy to detexmine the cause during the same hospitalization.Complications developed in 6.8％ selected cases.These was no septic shock nor death during the treatment.Conclusions Modem comprehensive non-surgical treatment is effective for most PGDU cases without serious complications,except for those with septic shock,severe intra abdominal infection and massive ascites.