术前未行颈动脉体瘤栓塞的患者手术后并发症的单中心回顾性研究
Outcomes of surgical treatment for carotid body tumor without preoperative embolization: a single-center retrospective study
摘要目的:观察和分析未术前栓塞颈动脉体瘤(carotid bodytomor, CBT)患者手术切除后的并发症发生情况。方法:按照严格的纳入排除标准,纳入本中心2011年1月至2016年12月确诊为CBT,行手术切除且未术前栓塞,2年内随访数据完善的101例患者。统计和分析其临床数据资料。结果:101例CBT患者的手术切除成功率为100%。按照Shamblin分型,患者围手术期主要的不良事件发生率:舌偏(Ⅰ:4例,36.4%; Ⅱ:8例,19.5%; Ⅲ:13例,26.5%),声音嘶哑(Ⅰ:1例,9.1%; Ⅱ:4例,9.8%; Ⅲ:7例,14.3%),吞咽困难(Ⅰ:0例;Ⅱ:2例,4.9%; Ⅲ:7例,14.3%),局部血肿(Ⅰ:0例;Ⅱ:0例;Ⅲ:1例,2.0%)。总体围手术期不良事件发生率:Shamblin Ⅰ型5例(45.5%),Ⅱ型14例(34.1%),Ⅲ型28例(57.1%)。术后2年随访发现,Shamblin Ⅰ型无不良事件;Shamblin Ⅲ型不良事件发生率多于Shamblin Ⅱ型,但差异无统计学意义( P>0.05)。CBT切除手术最容易损伤的三个神经是:舌下神经(21.9%),迷走神经(20.3%)和喉返神经(18.8%)。 结论:随访结果表明CBT患者手术切除前不进行术前栓塞术后并发症的发生率并不高,与患者预后无明显相关。
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abstractsObjective:To investigate the outcomes of surgical treatment for carotid body tumor(CBT) without preoperative embolization at our institution.Methods:101 patients undergoing surgical treatment for CBT without preoperative embolization from 2011 to 2016 were followed-up for 2 years.Results:Complete resection of the CBT was achieved in all 101 cases(100%). Post-operative adverse events(AEs) mostly observed during hospitalization were as tongue bias(Ⅰ: 4, 36.4%; Ⅱ: 8, 19.5%; Ⅲ: 13, 26.5%), hoarseness(Ⅰ: 1, 9.1%; Ⅱ: 4, 9.8%; Ⅲ: 7, 14.3%), dysphagia (Ⅰ: 0; Ⅱ: 2, 4.9%; Ⅲ: 7, 14.3%) and local hematoma(Ⅰ: 0; Ⅱ: 0; Ⅲ: 1, 2.0%). No other serious AEs were observed. The total incidence of AEs was 5(45.5%) in type Ⅰ patients, 14(34.1%) in type Ⅱ, and 28(57.1%) in type Ⅲ. At the end of 2 years of follow-up, there was no AEs in type Ⅰ patients. The number of patients with adverse events in type Ⅲ was greater than that in type Ⅱ ( P>0.05). Three most frequently injured cranial nerves were hypoglossal nerve(21.9%), vagus nerve(20.3%), and recurrent laryngeal nerve(18.8%). Conclusion:Surgical management without preoperative embolization for CBT patients does not increase the risk of complications nor is it related to prognosis.
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