摘要目的:总结开窗-分支胸主动脉腔内修复术（F/B-TEVAR）治疗复杂主动脉弓疾病患者并发症的危险因素。方法:回顾性分析2019年2月至2023年9月多中心接受F/B-TEVAR修复主动脉弓部病变的202例患者的临床及随访资料。结果:202例患者术后出现并发症46例（22.8%）。分析显示风险因素包括：主动脉粥样硬化斑块［ OR=2.843；95% CI（1.4~5.6）； P<0.01］、主动脉壁内血栓［ OR=2.358；95% CI（1.2~4.6）； P=0.011］、主动脉扩张［ OR=4.219；95% CI（1.6~11.3）； P<0.01］、脑卒中史［ OR=2.088；95% CI（1.1~4.1）； P=0.032］、吸烟史［ OR=2.680；95% CI（1.3~5.5）； P<0.01］、手术时长［ OR=1.9；95% CI（1.2~2.9）； P=0.042］。3D打印辅助技术应用［ OR=0.392；95% CI（0.2~0.9）； P=0.048］可以降低并发症发生率。 结论:主动脉粥样硬化斑块、主动脉壁内血栓、主动脉扩张、脑卒中史、吸烟史、手术时长是F/B-TEVAR术后发生并发症的独立危险因素，应用3D打印技术辅助能降低并发症发生率。

abstractsObjective:To review the risk factors for early and medium-term complications of fenestration-branch endovascular thoracic aortic repair (F/B-TEVAR) in patients with complex aortic arch disease.Methods:The clinical and follow-up data of 202 patients undergoing F/B-TEVAR treatment from Feb 2019 to Sep 2023 in these centers were retrospectively analyzed .Results:There were 46 cases suffering from postoperative complications (22.8%). The risk factors with statistical significance included aortic atherosclerotic plaque [ OR=2.843; 95% CI (1.4-5.6); P<0.01], aortic intramural thrombosis [ OR=2.358; 95% CI (1.2-4.6), P=0.011], the aortic dilatation [ OR=4.219; 95% CI (1.6-11.3), P<0.01], the history of stroke [ OR=2.088; 95% CI (1.1-4.1), P=0.032], smoking history [ OR=2.680; 95% CI: (1.3-5.5); P<0.01], duration of surgery [ OR=1.9; 95% CI: (1.2-2.9); P=0.042].While the application of 3D printing assistive technology [ OR=0.392; 95% CI: (0.2-0.9); P=0.048] was in a negative correlation with postoperative complication. Conclusions:The independent risk factors for complications after F/B-TVAR included aortic atherosclerotic plaque, aortic intramural thrombosis, the aortic dilatation, the history of stroke, smoking history,duration of surgery.The application of 3D printing technology can effectively reduce the complication rate.