摘要目的 分析肝肾联合移植36例的治疗效果及存活情况.方法 回顾性分析20022011年单中心施行的36例肝肾联合移植的临床资料.受者的年龄为(47.4±13.1)岁,术前4例曾接受过肝移植,7例曾接受肾移植.统计术后并发症发生情况及受者和移植物的存活情况.结果 存活受者随访47.9个月(29.1～115.7个月).术后1、3和5年受者存活率分别为88.7％、85.4％和81.4％;1、3和5年移植肝存活率分别为79.8％、76.3％和72.3％；1、3和5年移植肾存活率分别为85.7％、82.4％和78.2％.3例受者因严重胆道并发症进行了再次肝移植,1例受者因移植肾功能丧失进行了再次肾移植.结论 肝肾联合移植是治疗终末期肝病伴肾功能衰竭的有效方法,受者和移植物可获得良好的预后.

abstractsObjective To analyze the curative effects and survival results of combined liver kidney transplantation (CLKT).Methods From 2002 to 2011,the clinical data of 36 Chinese patients who underwent CLKT were retrospectively analyzed in our centre.The age of recipients was 47.4 ±13.1 years.Four patients had undergone liver transplantation and 7 patients kidney transplantations before CLKT, respectively. The complications and the survival were analyzed. Results The survival patients were followed up for 47.9 months (29.1 - 115.7).The cumulative 1-,3 and 5-year patient survival rate was 88.7％,85.4％ and 81.4％; The 1,3- and 5-year survival rate of liver graft was 79.8％,76.3％ and 72.3％; The 1-,3- and 5 year survival rate of kidney graft was 85.7％,82.4％ and 78.2％.Three patients underwent liver re-transplantation due to severe biliary complications,and one patient kidney re-transplantation due to renal allograft dysfunction.Conclusion CLKT is a effective treatment for end-stage liver disease with renal insufficiency and achieves excellent results.