摘要根据上海市杨浦区长白社区卫生服务中心数据库中2009年所有高血压患者使用的降压药物,整理出患者降压治疗方案,剔除所有治疗方案不确定者(包括换药过频方案不确定者及偶尔来本中心就诊尚不能确定方案者),进行统计分析.结果 显示,4102例高血压患者药物使用情况为:钙拮抗剂(CCB)占45.6%,血管紧张素转换酶抑制剂(ACEI)占16.0%,血管紧张素受体拮抗剂(ARB)占3.6%,β受体阻滞剂占9.0%,利尿剂4.7%,复方制剂占21.1%.降压方案为:使用单药的占68.0%,二联用药的占29.3%,三联用药的占2.6%,四联用药的占0.1%,其中二联用药方案中以CCB为基础的占75.8%,三联及四联用药方案均以CCB为基础组合而成.提示,本社区门诊高血压患者使用降压药物种类和联合降压方案基本符合国际高血压治疗指南,但是单一降压药物使用比例较高,联合降压的比例仍偏低.

abstractsThe antihypertensive treatment protocols of 4102 patients from the database of Changbai Community Health Service Center of Shanghai Yangpu District were analyzed.Patients with irregular drug treatment were excluded in the study.In 4102 hypertensive patients,45.6% took calcium channel blockers (CCB),16.0% took angiotensin converting enzyme inhibitors ( ACEI),3.6% took AT1-receptor blocker (ARB),9.0% took β-adrenergic receptor blockers,4.7% took diuretics and 21.1% took compound preparation.68% patients were in single-drug protocol,29.3% in two-drug,2.6% in three-drug and 0.1% in four-drug.In patients with two-drug protocol,75.8% was based on CCB; three-drug or four-drug protocols were also based on the combination of CCB.The results indicate that the treatment protocol for hypertensive patients in our community health service center basically meets the requirements of International Society of Hypertension Treatment Guidelines,but the proportion of the single drug use seems to be high,more combination of antihypertensive drug use should by proposed.