摘要回顾性分析我院行内镜检查为食管溃疡患者的临床病例资料及内镜特点，结果显示，50例食管溃疡患者中男39例，女11例（ P＜0.01）。青年6例，中年28例，老年16例，中年及老年患病高（ P＜0.01）。良性29例，恶性16例，不明5例，良性食管溃疡病因中反流性食管炎13例。内镜下食管溃疡位于食管上段7例，食管中段11例，食管下段32例，食管下段发病比例高（P＜0.01）。各性别、年龄、溃疡部位、溃疡数量组间食管溃疡良恶性构成差异无统计学意义（P＞0.05），但内镜表现为深、巨大（≥2.5 cm）及不规则溃疡者为恶性溃疡的可能性大（ P＜0.01）。提示食管溃疡良性居多，主要病因为反流性食管炎。食管溃疡好发于中老年男性及食管下段。食管溃疡良恶性与性别、年龄、溃疡部位及数量无明显关系，但与溃疡深浅、大小及形态相关。

abstractsThe clinical features and endoscopic findings of 50 with esophageal ulcers were retrospectively reviewed.The ratio of male to female was 3.5∶1 (39∶11, P<0.01).The age distribution:6 cases were ≤35 y, 28 cases were 35-59 y and 16 ≥60 y ( P<0.01).Twenty nine cases were benign , 16 cases were malignant and 5 cases were uncertain.Reflux esophagitis was the main etiology of benign&nbsp;esophageal ulcers.The ulcers were located at upper ,middle and lower esophagus in 7, 11 and 32 cases, respectively (P<0.01).There were no significant differences of age , sex, location and amount of ulcers between benign and malignant esophageal ulcers ( P >0.05 ).However deep , large (≥2.5 cm ) and irregular esophageal ulcers were more likely to be malignant ( P <0.01 ).The clinical and endoscopic findings reveal that the malignancy of esophageal ulcer is correlated with the size , depth and shape of the lesions.