摘要糖尿病酮症酸中毒（DKA）是糖尿病严重、急性并发症之一。社会人口老龄化及生活方式的改变，老年DKA和肥胖型DKA患者增多。老年DKA患者因治疗依从性差、症状不典型、合并疾病多，具有易患病、难诊断、难治疗的特点。肥胖型DKA青年男性最多见，起病前常有含糖软饮料饮用史，经治疗后胰岛功能多能恢复。新型治疗药物及方案可诱发非高血糖型DKA。通过临床数据分析，归纳老年及肥胖型2型糖尿病患者DKA的特点及治疗探索，以提高临床识别及初步处理DKA的能力。

abstractsDiabetic ketoacidosis (DKA) is one of the most serious acute metabolic complications of diabetes.With the aging of population and the change of lifestyle in China, DKA is common in elderly or obese patients. The elderly patients are prone to DKA due to the poor treatment compliance, atypical symptoms and more complicated diseases; while DKA is more common in obese young men who excessively consumed sugary soft drinks before the onset of illness, their islet function can be restored after appropriate treatment. The application of some new therapeutic drugs and treatment options may induce euglycemic DKA. Through clinical data analysis, understanding the disease characteristics and following the treatment standards, the management of DKA in elderly or obese type 2 diabetic patients can be improved.