影像组学对肝细胞癌经动脉化疗栓塞术疗效预测的应用进展
Advances in the application of radiomics in predicting outcomes after transarterial chemoembolization for hepatocellular carcinoma
摘要肝细胞癌是常见的恶性肿瘤之一,多数肝细胞癌患者在临床发现时已处于中期阶段,经动脉化疗栓塞术是治疗中期肝细胞癌的标准治疗方法。由于肿瘤的高度异质性,准确预测肝细胞癌患者经动脉化疗栓塞术后的疗效仍是临床难点之一。影像组学作为一种新兴技术,它不仅可以无创地反映肿瘤的异质性,还能通过分析肿瘤微环境的改变监测、评估以预测肿瘤进展,指导患者的个性化治疗,延长患者的生存时间。本文对影像组学在预测肝细胞癌经动脉化疗栓塞术疗效的应用研究进展进行综述。
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abstractsHepatocellular carcinoma is one of the common malignant tumors, and most patients with hepatocellular carcinoma are already in the middle stage at the time of clinical detection, transarterial chemoembolization is the treatment of choice for mid-stage hepatocellular carcinoma.Due to the high degree of tumor heterogeneity, accurately predicting the outcome of patients with hepatocellular carcinoma after transarterial chemoembolization remains one of the difficulties in clinical practice.As an emerging technology, radiomics can not only reflect tumor heterogeneity non-invasively, but also monitor, evaluate and predict tumor progression by analyzing changes in the tumor microenvironment to guide patients′ personalized treatment and prolong their survival time.This article reviews the progress of the application of radiomics in predicting the efficacy of transarterial chemoembolization for hepatocellular carcinoma.
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