冠状动脉非阻塞性心肌梗死的心磁图特征初探
A preliminary study on the magnetocardiographic characteristics of myocardial infarction with non-obstructive coronary artery disease
摘要该研究为横断面研究。纳入2021年7月至2022年8月上海交通大学医学院附属第六人民医院住院的冠状动脉非阻塞性心肌梗死(MINOCA)患者(MINOCA组),同期纳入心脏检查正常的人群作为对照(对照组)。通过电子病历系统收集入选者的一般临床资料和心磁图检查结果。MINOCA组共入选患者6例,对照组共入选78人,按年龄、性别、体重指数、职业、婚姻状况进行匹配后,最终两组各入选5人。以对照组作为参照,发现MINOCA组患者QRS段存在QR转动异常,TT段正、负磁极离散改变,电流方向紊乱。两组人群共有35个心磁图参数差异有统计学意义,涉及TT间期、QRS波段、RS间期、QR间期等多个波段。该研究初步探索了MINOCA的心磁图特征,可为建立心磁图MINOCA诊断模型提供参考。
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abstractsIt was a cross-sectional study. Six myocardial infarction patients with non-obstructive coronary artery disease (MINOCA group) admitted to Shanghai Sixth People′s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from July 2021 to August 2022 were enrolled in the study and 78 healthy subjects were selected as control group. The patients and healthy controls were selected with 1∶1 propensity score matching according to age, gender, body mass index, occupation and marriage status; and 5 study subjects of each group were finally enrolled in the study. The general clinical data and magnetocardiographic (MCG) results were collected from the hospital′s electronic medical record system. Compared with control group, MINOCA group showed abnormal QR rotation, discrete changes in positive and negative magnetic poles in TT segment, and disordered current direction. The analysis of MCG data revealed 35 parameters with statistically significant difference between the two groups, involving TT interval, QRS complex, RS interval and QR interval. This study explored the magnetocardiographic characteristics of MINOCA, which suggest that MCG may be conducive for diagnosis of MINOCA in the future.
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