摘要目的 调查川南地区癫痫住院患者总体病因分布情况、不同年龄段癫痫住院患者的病因分布,以指导临床诊疗工作.方法 收集2014年8月至2017年7月我院确诊的癫痫住院患者完整的病案资料,采用国际抗癫痫联盟2017年修订的癫痫病因分类方法进行总体病因分类并分析不同年龄阶段的病因分布.结果 共纳入癫痫患者665例,癫痫总体病因分布为结构性病因(398例,59.8％)、感染病因学(122例,18.3％)、代谢性病因(12例,1.8％),免疫性病因和遗传性病因少见.儿童期、青少年期癫痫病因以不明原因、病毒感染、颅内血管畸形及皮质发育障碍为主,成年期以颅脑外伤为病因者明显增多(68/380,18.0％),脑卒中为病因者占18.7％(71/380),脑肿瘤为病因者占17.1％(65/380).老年期癫痫患者以脑卒中和其他脑血管疾病为主(106/178,59.6％),其次是颅脑创伤(17/178,9.6％)和肿瘤性疾病(17/178,9.6％).结论 川南地区住院癫痫患者的病因主要为结构性病变,即以脑血管病、颅内感染、脑外伤、肿瘤最为常见,但不同年龄有不同病因分布.

abstractsObjective To investigate the distribution of the general etiology of hospitalized patients with epilepsy in Southwest China and the etiological distribution of epilepsy patients of different ages.Methods The complete medical records of hospitalized patients with epilepsy diagnosed in our hospital from August 2014 to July 2017 were collected,the overall cause of the disease was classified,and the etiology distribution of different age groups was analyzed.Results A total of 665 eligible patients were enrolled.The overall etiology of epilepsy was structural (398/665,59.8％),infectious (122/665,18.3％) and metabolic (12/665,1.8％).The etiological and genetic causes were rare.Childhood and adolescent epilepsies were mainly due to unknown,viral infection,intracranial vascular malformations and cortical development disorders.As for etiology in adults,traumatic brain injury accounted for 18.0％ (68/380),cerebral hemorrhage accounted for 18.7％ (71/380),and brain tumors accounted for 17.1％ (65/380).Elderly patients with epilepsy accounted for 59.6％ (106/178) of stroke and other cerebrovascular diseases,followed by traumatic brain injury (17/178,9.6％) and neoplastic disease (17/178,9.6％).Conclusions The etiology of hospitalized epilepsy patients in Southern Sichuan is mainly structural lesions.And cerebrovascular disease,intracranial infection,brain trauma and tumor are the most common etiologies,but there are different etiologies at different ages.