水痘-带状疱疹病毒感染后中枢和周围神经联合脱髓鞘疾病1例
Combined central and peripheral demyelination after varicella-zoster virus infection: a case report
摘要中枢和周围神经联合脱髓鞘疾病(CCPD)是一种少见的自身免疫性疾病,其发病机制尚不明确。本文报道1例确诊的水痘-带状疱疹病毒(VZV)感染后发病、血清抗神经束蛋白155 IgG4抗体阳性的CCPD患者,其对激素和丙种球蛋白治疗效果良好。本文总结该患者的临床特点、探讨其可能的发病机制,旨在提高临床医师对VZV感染后CCPD的认识。
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abstractsCombined central and peripheral demyelination (CCPD) is a rare autoimmune disease and its action mechanism remains unknown. This article described a case of CCPD with anti-neurofascin 155 IgG4 antibodies after varicella-zoster virus (VZV) infection who was recovered after steroids and intravenous immunoglobulin treatments. The clinical characteristics of this patient were summarized and the possible pathogenesis was discussed, so as to provide information of CCPD after VZV infection for clinicians.
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