摘要路易体痴呆（DLB）是神经系统退行性疾病中第二大痴呆类型，最新的中国路易体痴呆诊断与治疗指南将脑电图异常定义为临床诊断的支持性生物标志物。DLB患者的癫痫发作和癫痫样放电逐渐引起大家的关注和研究，越来越多的研究证据表明DLB和癫痫之间存在相关性。但DLB患者癫痫发作的识别及诊断仍面临挑战，并且除临床癫痫发作外，亚临床癫痫活动也是DLB的重要研究内容。DLB癫痫发作潜在的病理机制仍不明确。本综述总结了目前癫痫与DLB之间的联系、潜在病理机制和今后可能的研究方向，提醒临床医师在诊疗过程中关注DLB患者的癫痫及亚临床癫痫活动，早期识别并及时干预。

abstractsDementia with Lewy bodies (DLB) is the second most prevalent type of dementia among neurodegenerative disorders. The latest guideline for diagnosis and treatment of DLB in China has defined electroencephalography abnormalities as one of the supportive biomarkers. Seizures and epileptiform discharges in patients with DLB are gradually attracting attention and research, and there is increasing evidence of the correlation between DLB and epilepsy. However, the identification and diagnosis of seizures in DLB patients are challenging. In addition to clinical seizures, subclinical epileptiform activity is also an important part in DLB research. The underlying pathological mechanism of DLB epileptic seizures is still unclear. The current connection, potential pathological mechanisms, and possible future research directions between epilepsy and DLB were summarized in this review. The current relationship between epilepsy and DLB, potential pathological mechanisms and possible future research directions were summarized in this review, reminding clinicians to pay attention to the epilepsy and subclinical epilepsy activity in the diagnosis and treatment process, early identification, and timely intervention of the DLB patients.