摘要Autism spectrum disorder (ASD) is a serious neurodevelopmental disorder, the etiology and mechanism of which are not yet clear. Studies have shown that folate deficiency can lead to abnormalities in the de-velopment of the central nervous system. Patients with autism spectrum disorders develop folate-alpha recep-tor autoantibodies. Folate-alpha receptor autoantibodies block folate transport, leading to a deficiency of folate in nerve tissues. Folate is effective in treating patients with folate-alpha receptor autoantibodies.
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