摘要Objective:To investigate clinical signif-icance of the effects of smoking on blood lipids,C-reac-tive protein,and homocysteine in young ischemic stroke patients.Methods:The clinical data of 423 young stroke patients in the department of neurology at Taihe Hospi-tal in Shiyan City,China were retrospectively analyzed,including age,gender,drinking history,family history,and atrial fibrillation history.Patients were divided into two groups according to whether they smoked,and the blood lipids,C-reactive protein,and homocysteine were compared between groups.Results:The proportion of smokers was 41.83%.The levels of total cholesterol,tri-glycerides(TG),low density lipoprotein(LDL),and ho-mocysteine were higher in patients who smoked than in those who did not(P＜0.05).High density lipoprotein(HDL)was lower in the smoking group(P＜0.05).C-re-active protein test results were divided into groups ac-cording to whether the levels exceeded the normal range or not,and no correlation was found between C-reactive protein levels and smoking(P＞0.05).Conclusion:Total cholesterol,TG,LDL,HDL,and homocysteine were sig-nificantly different between stroke patients who smoked and those who did not.We therefore suggest that smok-ing cessation take place as soon as possible and that it be avoided entirely in order to reduce the incidence of atherosclerosis and stroke.