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Primary imaging features and recent application of PET tracers in cerebral amyloid angiopathy

摘要Cerebral amyloid angiopathy (CAA) is a small vessel disease of the brain characterized by the progressive deposition of amyloid-β (Aβ) plaques in the walls of cerebral blood vessels. It presents with a sub-tle course and sudden onset,and currently,there are no specific therapeutic interventions available. Accurate di-agnosis of CAA could enable targeted interventions in the early stages of the disease,potentially mitigating the disease's effects. Herein,we review the primary imaging biomarkers used in the diagnosis of CAA,including their mechanisms,imaging characteristics,and significance. We also provide an interpretation of the latest version (v2.0) of the Boston criteria,which are commonly used in the clinical diagnosis of CAA. Additionally,this study introduces various positron emission tomography (PET) tracers for CAA and reviews their application values in the diagnosis of CAA.

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作者 Wei Zheng [1] Chongchong Gao [2] Zehui Wu [1] 学术成果认领
作者单位 Beijing Institute of Brain Disorders,Laboratory of Brain Disorders,Ministry of Science and Technology,Collaborative Innovation Center for Brain Disorders,Capital Medical University,Beijing 100069,China [1] Department of General Surgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China [2]
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DOI 10.3868/j.issn.2096-0689.2024.02.003
发布时间 2024-12-16(万方平台首次上网日期,不代表论文的发表时间)
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