摘要This review discusses the functions of blood vessels such as coagulation,regulation,immunity,endocrinology,and nerve conduction from a new perspec-tive and suggests that hypoxia plays a common role in the changes in vascular function in various cardiovascu-lar and cerebrovascular diseases. Therefore,it is oxygen therapy regulation may be a particularly beneficial means by which to regulate vascular function due to its low risk of harm and ease of implementation. Further,the authors have identified a link between vascular function and dis-eases caused by endogenous hypoxia and analyzed it in depth. The potential effects of hypoxia regulation schemes such as hyperxia,hyperoxic-hypoxia alternations,hypox-ia preconditioning,and intermittent hypoxia on vascular function are also discussed,and we present theoretical support for targeted vascular therapy.