摘要Lipoprotein(a)[Lp(a)]is a unique plas-ma lipoprotein particle with a distinct structure that has garnered significant research attention due to its strong association with various cerebrovascular diseases.Recent studies underscore elevated Lp(a)levels as a critical risk factor,with multiple Lp(a)-targeted therapies advancing through clinical trials.This review explores the structural,functional,and genetic features of Lp(a),its connection to cerebrovascular diseases,and the latest therapeutic strategies aimed at reducing its impact.By consolidat-ing these advancements,we aim to provide new insights for Lp(a)-centered research and propose innovative ap-proaches for cerebrovascular disease prevention and man-agement.
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