摘要目的 总结颅底浆细胞瘤的临床、影像、病理学特征,旨在提高对该病的认识.方法 回顾性分析经手术及病理证实的7例颅底浆细胞瘤的临床资料,并复习相关文献.结果 颅底浆细胞瘤血供丰富,术中易大量出血.本组近全切2例,大部切除5例.随访12-24个月,3例进展为多发骨髓瘤.结论 颅底浆细胞瘤罕见,神经影像学缺乏特异性表现,术前多诊断为脊索瘤或颅底恶性肿瘤,确诊需根据病理结果.不同类型的浆细胞瘤治疗方案不同,手术结合放疗或化疗是首选治疗方案.

abstractsObjective To summarize clinical manifestation,neuroradiological characteristics and pathological features of plasmacytomas of skull base.Methods A retrospective review was conducted in 7patients with surgically and pathologically verified plasmacytomas of skull base.Results Plasmacytomas of skull base was a kind of highly vascular tumor resulting in intro-operative excessive blood loss.Subtotal removal was achieved in 2 cases,and partial resection in 5 cases.After 12-24 months of follow-up period,3 cases developed to multiple plasmacytoma.Conclusion Plasmacytomas of skull base are rare.Neuroradiological findings generally lack specificity.A preoperative diagnosis is often chordoma or skull-base malignant tumor.An accurate diagnosis depends on histopathology.The treatment options are different for different entities.The primary therapy mode for plasmacytomas is surgery followed by radiation or chemotherapy.