摘要目的 探讨小骨窗显微镜下手术治疗儿童脑型肺吸虫病(CP)的临床疗效.方法 回顾性纳入重庆三峡中心医院儿外科2015年1月至2018年2月采用小骨窗显微手术治疗的25例CP患儿.所有患儿均因脑出血入院.术后全部患儿服用吡喹酮4～6个疗程.根据日常生活能力(ADL)分级标准评估手术疗效.结果 25例患儿均无手术相关并发症.随访3～36个月(中位数为18个月),均预后良好,其中ADL分级Ⅰ级者24例,Ⅱ级者1例.血液检查显示,嗜酸性粒细胞数及其比率逐渐降低,至术后2～3个月时基本降至正常.随访期均未见复发.结论 小骨窗显微术治疗CP疗效确切,并发症发生率低.

abstractsObjective To investigate the clinical efficacy of small skull window microsurgery for cerebral paragonimiasis in children.Methods The retrospective study included 25 children with cerebral paragonimiasis who underwent small skull window microsurgery at Department of Pediatric Surgery,Chongqing Three Gorges Central Hospital between January 2015 and February 2018,and all children had intracerebral bleeding at admission and had praziquantel for 4-6 courses after surgery.The surgical treatment effects and outcomes were analyzed and evaluated according to activity of daily living (ADL).Results Among 25 cases,there was no operative complications.All the patients recovered well in 3-36 months at follow-up (median:18 months).According to ADL,the outcomes of 25 cases were graded as follows:level Ⅰ in 24 cases and level Ⅱ in 1.The number and ratio of eosinophils were gradually decreased in blood routine test,and those were at approximately normal levels after 2-3 months of operation.There was no recurrence in this study.Conclusion The small skull window microsurgery for children's cerebral paragonimiasis seems to have definite clinical effect and relatively low rates of complications.