摘要目的:初步探讨Tubridge血流导向装置(FD)治疗颈内动脉夹层动脉瘤的安全性和有效性。方法:回顾性分析2013年1月至2020年12月海军军医大学第一附属医院脑血管病中心采用Tubridge FD治疗且随访时间≥6个月的19例颈内动脉夹层动脉瘤患者的临床资料。19例患者共19个动脉瘤，其中颈内动脉颈段4个、岩骨段3个、破裂孔段2个、海绵窦段4个、床突上段1个、眼段2个、交通段3个。采用改良Rankin量表评分(mRS)评估患者围手术期及随访时的神经功能；术后即刻及随访时采用O′Kelly-Marotta (OKM)分级评估动脉瘤的栓塞程度。结果:19个动脉瘤共置入22枚Tubridge FD，其中3个动脉瘤置入2枚Tubridge FD。置入成功率为100%。所有Tubridge FD均贴壁良好，载瘤动脉通畅，术中未发生缺血或出血等不良事件。19个动脉瘤的即刻OKM分级：A级9个、B级3个、C级1个、D级6个。所有患者围手术期无不良事件发生，出院时mRS均为0分。其中18例患者接受临床随访，随访时间[ M( Q1， Q3)]为24.0(14.3，41.0)个月，mRS均为0分。14例患者(14个动脉瘤)接受影像学随访，随访时间[ M( Q1， Q3)]为8.0(6.0，10.8)个月，OKM分级：C级4个、D级10个。 结论:Tubridge FD治疗颈内动脉夹层动脉瘤的技术成功率高，即刻疗效满意，中期随访动脉瘤永久闭塞率高，且并发症的发生率较低，但长期疗效及安全性有待于进一步观察。

abstractsObjective:To investigate the safety and efficacy of the Tubridge flow diverter (FD) in the treatment of internal carotid artery dissection.Methods:The clinical data of 19 patients with internal carotid artery dissection treated with the Tubridge FD and followed up for ≥ 6 months in the Cerebrovascular Disease Center of the First Affiliated Hospital of Naval Military Medical University from January 2013 to December 2020 were analyzed retrospectively. There were 19 aneurysms in 19 patients, including 4 cases of carotid segment of internal carotid artery, 3 cases of petrosal segment, 2 cases of ruptured foramen segment, 4 cases of cavernous sinus segment, 1 case of supraclinoid segment, 2 cases of ocular segment and 3 cases of communicating segment. Modified Rankin Scale score (mRS) was used to evaluate the neurological function during perioperative and follow-up; O′Kelly Marotta (OKM) grade was used to evaluate the embolization degree of aneurysms immediately after operation and during follow-up.Results:A total of 22 Tubridge FDs were implanted in 19 aneurysms and 2 Tubridge FDs were placed in 3 aneurysms. The success rate of implantation was 100%. All Tubridge FDs were deloyed well, the parent artery was unobstructed, and no adverse events such as ischemia or bleeding occurred during the operation. The immediate OKM grades of 19 patients were grade A in 9 cases, grade B in 3 cases, grade C in 1 case and grade D in 6 cases. No adverse events occurred during perioperative period, and the mRS score was 0 at discharge in all cases. Eighteen patients received clinical follow-up for [ M ( Q1, Q3)] 24.0 (14.3, 41.0) months, with a mRS score of 0. Fourteen patients (14 aneurysms) received imaging follow-up for [ M ( Q1, Q3)] 8.0 (6.0, 10.8) months. The OKM rating results were grade C in 4 cases and D in 10 cases. Conclusions:The Tubridge FD has high technical success rate, satisfactory immediate effect, high occlusion rate of aneurysms in mid-term follow-up and low incidence of complications, but the long-term efficacy and safety need to be further observed.