摘要目的 调查并评价未经治疗的未破裂颅内动脉瘤(UIA)患者的精神心理问题.方法 选择上海同济大学附属同济医院神经外科自2008年1月至2011年1月就诊的70例未经治疗的UIA患者和48例健康体检者(对照组)进行调查问卷,应用症状自评量表(SCL-90)、抑郁自评量表(SDS)及焦虑自评量表(SAS)评价未经治疗的UIA患者的精神心理状况.结果 与对照组比较,未经治疗的UIA患者组SCL-90中躯体化、抑郁、焦虑、恐怖四项因子分及总分均较高,未经治疗的UIA组患者更易抑郁、焦虑,差异均有统计学意义(P＜0.05)；内向性格抑郁发生率高于外向和中性性格,外向性格患者焦虑发生率低于中性及内向性格,大学文化程度患者抑郁、焦虑发生率低于高中及初中文化程度患者,差异均有统计学意义(P＜0.05)；多因素Logistic回归分析显示性格、文化程度是影响未经治疗UIA患者抑郁、焦虑的独立危险因素.结论 未治疗的颅内动脉瘤患者容易出现抑郁或焦虑,文化程度低、内向型的患者表现更明显.

abstractsObjective To assess and investigate the psychological problems of patients with untreated un-ruptured intracranial aneurysm(UIA).Methods Seventy patients with untreated UIA,admitted to our hospital from January 2008 to January 2011,and 48 healthy controls were evaluated by Symptom Checklist-90(SCL-90),Self-rating Depression Scale(SDS)and Self-Rating Anxiety Scale (SAS).Results In the SCL-90,the sub-scores of somatization,depression,anxiety and terror,and the total scores of patient group were significantly higher than those of controls(P＜0.05); as compared with the controls,these patients were more likely having depression and anxiety(P＜0.05).The depression and anxiety in introverted patients and poor education patients were more serious as compared with those in other types (P＜0.05); regression analysis suggested that the indepent risks of psychology included education levels and personality types.Conclusion The untreated UIA patients will be prone to depression or anxiety,and poor educational or introverted patients are more likely to have depression or anxiety.