摘要癫痫是神经元异常放电所致的慢性反复发作性神经功能障碍性疾病,颢叶癫痫(TLE)是最常见的癫痫类型.长期的癫痫活动传播会造成颞叶外广泛脑区的结构及功能损害.随着神经系统检查技术的不断发展,结构和功能检查方法的应用揭示了癫痫复杂的结构、功能及代谢网络的改变,为进一步探索癫痫发病机制和改善癫痫治疗效果提供了重要的帮助.本文主要围绕不同检查方法显示的颞叶癫痫患者脑部网络结构、功能及代谢改变研究进展进行综述.

abstractsEpilepsy is a chronic repetitive paroxysmal neurological disorders that caused by abnormal discharge of neurons.Temporal lobe epilepsy is the most common type of epilepsy,and long-term spread of seizures can damage the structure and function of the brain in the wide outside of temporal lobe regions.With the continuous development of the nervous system inspection technology,application of structural and functional examinations reveals the changes of complicated structure,function and metabolism of the epilepsy network.It helps us to explore the further pathogenesis of epilepsy and improve the effectiveness of treatment.Here,we mainly review the recent advance in the changes of structure,function and metabolism of the temporal lobe epilepsy network displayed by different inspection methods.