摘要目的 应用经颅多普勒超声(TCD)评价健康成人颈动脉压迫试验(压颈试验)前后大脑中动脉(MCA)的血流变化. 方法 选择深圳市宝安区中心医院体检中心及各科室自2015年10月至2016年8月的健康体检者或进修学员99例,其中男性62例,女性37例;不大于40岁者35例(青年组),大于40岁者64例(中老年组).应用TCD观察不同年龄、性别受试者压颈试验前、后MCA收缩期峰值血流速度(Vp)、平均血流速度(Vm)、舒张末期血流速度(Vd)及Vp、Vm、Vd代偿率的差异. 结果 压颈试验前、后,青年组受试者MCA的Vp、Vm、Vd及Vm、Vd代偿率均高于中老年组,差异有统计学意义(P＜0.05);2组受试者Vp代偿率比较差异无统计学意义(胗0.05);压颈试验前、后,男性、女性受试者MCA的Vp、Vm、Vd及代偿率比较差异均无统计学意义(P＞0.05).结论 TCD能初步评价健康成人压颈试验后颅内动脉侧支循环代偿后MCA的血流效果,青年平均血流速度与舒张末期血流速度的代偿效果好于中老年人.

abstractsObjective To explore the middle cerebral artery (MCA) blood flow changes in healthy adults before and after carotid artery compression test by transcranial Doppler ultrasound (TCD).Methods Ninety-nine normal healthy adults,including 62 male and 37 female,were chosen in our study;they were divided into young group (＜40 years,n=35) and elderly group (＞40 years,n=64).The differences of peak level of MCA systolic blood flow velocity (Vp),mean blood flow velocity (Vm) and end diastolic blood flow velocity (Vd),and their compensation rates before and after oppression of the ipsilateral carotid artery were compared between patients of different ages and gender by TCD.Results The Vp,Vm and Vd,and the Vm and Vd compensation rates in the young group before and after oppression were significantly higher than those in the elderly group (PP＜0.05).The Vp,Vm and Vd,and their compensation rates before and after oppression showed no significant differences between male and female subjects (P＞0.05).Conclusion TCD can evaluate the effect of MCA blood flow on the collateral artery after compression carotid artery test;the compensatory effect of Vm and Vd in the young group is significantly higher than that in the elderly group.