摘要硬膜外脊髓电刺激（eSCS）是一种新兴的神经调控技术，其可通过激活感觉传入纤维、增强脊髓内神经网络的整合能力、优化脑-脊髓的信息传递、诱导脑-脊髓神经回路重塑等改善脊髓损伤、帕金森病、脑卒中患者的运动功能障碍。本文围绕eSCS的作用机制，电极植入和刺激参数，及其在脊髓损伤、帕金森病和脑卒中等疾病中的应用研究进展进行综述，以期为eSCS的临床应用提供参考。

abstractsEpidural spinal cord stimulation (eSCS) represents an emerging neuromodulation technology that ameliorates motor dysfunction in patients with spinal cord injury, Parkinson's disease, and stroke by activating sensory afferent fibers, enhancing spinal cord neural network integration, optimizing brain-spinal cord information transmission, and inducing neural plasticity. This article reviews the mechanism, electrode implantation, and stimulation parameter of eSCS, and application of eSCS in spinal cord injury, Parkinson's disease, and stroke, aiming to provide valuable insight for its clinical implementation.