摘要异体皮移植至今已经有近150年的历史,是修复大面积深度烧伤创面的关键措施之一.异体皮暂时存活覆盖创面,为最终自体皮修复创面提供宝贵机会.作为我国烧伤外科修复特大面积深度烧伤创面的主要方法——微粒皮移植技术和嵌皮技术都以异体皮移植为基础.近年来,由于异体皮来源困难,国内的许多烧伤中心出现“寸皮难求”的现象,严重影响了临床救治效果.器官获取组织和异体皮库建设将有望成为解决异体皮来源及质量问题的合法途径,而成功研制理想的组织工程皮肤是根本解决措施.

abstractsAllogeneic skin grafting has a history of nearly 150 years and is one of the key measures to repair extensive deep burn wounds.Allogeneic skin survives temporarily to cover the wound,providing a valuable opportunity for the ultimate wound repair using autografts.As the main methods for the repair of extensive deep burn wounds in China,both the microskin grafting technique and inlay skin grafting technique are based on allogeneic skin grafting.Since allogeneic skin is hardly available in recent years,many burn centers are in extreme lack of allogeneic skin,which seriously hampers clinical burn care.Organ Procurement Organization and allogeneic skin banks may be legal means of solving the problems of source and quality of allogeneic skin,and the successful development of ideal engineered skin is the fundamental solution to burn care without allogeneic skin grafting in the future.