摘要N 6-甲基腺嘌呤（m 6A）作为一种转录后修饰广泛存在于真核生物中，该种修饰受到甲基转移酶和去甲基化酶的动态可逆性调控，并通过m 6A结合蛋白参与调节生物学效应。近来研究表明，m 6A可参与胚胎皮肤形态发生、创面修复以及炎症反应、血管生成和纤维化等病理生理过程。该文概述了m 6A及其相关蛋白在创面修复相关病理生理进程中的作用，以期为创面修复的治疗策略提供新的理论依据。

abstractsN 6-methyladenosine (m 6A) exists widely in eukaryotes as a post-transcriptional modification. This modification is dynamically and reversibly regulated by methyltransferases and demethylases, and is involved in regulating biological effects through m 6A binding proteins. Recent studies have elucidated that m 6A is involved in embryonic skin morphogenesis, wound repair, and pathophysiological processes such as inflammatory response, angiogenesis, and fibrosis. This review summarizes the role of m 6A and its related proteins in the related pathophysiological processes of wound repair, so as to provide a new theoretical basis for the treatment strategy of wound repair.