摘要负压伤口疗法（NPWT）是一种利用持续性真空负压管理创面的方法，被广泛用于各种创面的治疗。局部应用NPWT技术可清除创面渗出物，减少细菌感染，刺激血管和肉芽组织形成等，为游离皮瓣移植提供良好的基底。然而，对于游离皮瓣移植术后是否行NPWT存在争议。研究表明，NPWT联合游离皮瓣移植治疗具有促进创面愈合、减少并发症的作用；在皮瓣供区创面使用NPWT可以减小创面张力，促进创面愈合，还能改善色素沉着。该文对NPWT在游离皮瓣移植术中的临床应用相关文献进行总结，为两者的联合应用提供理论依据。

abstractsNegative pressure wound therapy (NPWT) is a therapy that utilizes continuous vacuum negative pressure to manage wounds, and it is commonly employed in treating various wounds. The local application of NPWT technology is helpful in removing wound exudate, decreasing bacterial infection, and stimulating the formation of blood vessels and granulation tissue, thus providing a good base for free flap transplantation. However, there is controversy over whether NPWT should be performed after free flap transplantation. Researches showed that NPWT combined with free flap transplantation could promote wound healing and reduce complications. Additionally, applying NPWT in the wounds of flap donor areas can decrease wound tension, promote wound healing, and improve pigmentation. This paper aims to review literature related to the clinical use of NPWT in free flap transplantation, providing a theoretical basis for their combined application.