摘要随着临床上应用的金属植入物的不断增多,对植人物本身的结构要求也随之增高.3D打印技术飞速发展和医工交互的深入也使复杂结构的制造成为可能.在此基础上,基于有限元分析技术的结构拓扑优化逐步发展并极大地改善了植入物的生物力学性能.该综述介绍了应用拓扑优化技术进行植入物结构设计的理念和案例,并以颌面外科、骨科等研究为主线,对拓扑优化技术在医用植入物方面的研究和应用现状进行归纳总结.拓扑优化在骨科领域的应用最广泛,分别在关节假体、创伤内固定物以及脊柱植人物的结构设计中取得了理论和实践的双重进步.本文最后针对植入物的拓扑优化设计,展望未来医用金属植入物的研究趋势.

abstractsAs an increasing need for metal implant species and quantities in the clinical application,the demands of structure for the implants have been increased,accompanying the rapid development of 3D printing technology and the progress of medical combination with engineering also made it possible to fabricate complex implants.On this basis,the topology optimization of structure in the finite element analysis technique has been developed gradually,and the application of this technique has greatly improved the biomechanical properties of implants.This review introduces the applications of topology optimization technology in implant structure design,and summarizes the researches of topology optimization technique in the field of medical implant mainly on the department of maxillofacial surgery and orthopedics.In the field of orthopedics,topology optimization technique is most widely used,and in the structural design of joint prosthesis,internal fixation and spinal implant,the obvious progress was obtained in both theory and practice.Finally,the paper put forward the prospect of the trend for the topology optimization design of metal implants in the future.