摘要本文对6例维持性血液透析（CHD）的病人进行无醋酸盐生物滤过治疗（AFBF）。透析中使用聚砜膜透析器、容量平衡系统的透析机和无醋酸盐的透析液，并且以21~25 ml/分速度直接注入1.5%碳酸氢钠溶液。结果表明：1）透析耐受性好、食欲和全身状况明显改善。2）血浆肌酐、尿素氮、尿酸、磷和β 2-微球蛋白清除率更高。3）透析中避免发生低氧血症。指出AFBF具有血液透析滤过和碳酸氢盐透析的双重优点，是一种简便、安全、短时、高效无明显副作用的碳酸氢盐透析的替代疗法。

abstractsSix patients previously hemodialyzed (HD) were treated with AFBF. In this AFBF scheme we used a polysulfone dialyzer (1.25 m 2) and a dialysis machine with a volumetric fluid-balancing system and a dialysate containing (mmol/L): Na 139, K 2, Ca 1.75, mg 0.5, Cl 145.5. During dialysis (180~200 min) 21-25 ml/min of 1.5% sodium bicarbonate was pumped directly to the venous drip chamber The results showed: 1) excellent intradialytic tolerance significant improvement of appetite and general well-being; 2) higher clearance of lasma creatinine, urea, uric acid, phosphate and β 2 microglobulin; 3) avoidence of intradialytic hypoxemia. AFBF has the advantages of hemodiafiltration and bicarbonate dialysis, i.e. short time, high efficiency, low side effect, simple and safe alternative to bicarbonate dialysis.