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三十七年来北京儿童医院肾小球疾病类型的变化

Changing pattern of glomerular disease at Beijing children's hospital

摘要1992年中国北京儿童医院对住院的内科患者进行了分析,其中肾脏疾病505例,占儿内科住院患者数(6,885例次)的7.3%。急性肾小球肾炎占30%,肾病综合征占28%,紫癜性肾炎占16%。肾脏疾病的病死率是0.4%(2/505)。随访表明153例急性肾小球肾炎都康复或改善。124例单纯性肾病综合征,91%完全缓解或部分缓解。278例过敏性紫癜中,81例(29%)并肾炎。观察表明自1956年以来,急性肾小球肾炎明显减少,而肾病综合征却显著增多;虽然过敏性紫癜患者数呈逐年增多之趋势,但紫癜性肾炎的发病率37年来始终是29%。

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abstractsCurrent clinical experience with glomerular disease at a pediatric referral center in Beijing, China, was reviewed. In 1992, renal disorders accounted for 505 of a total 6885 (7.3%) pediatric medical discharges. Acute glomerulonephritis accounted for 30% of renal diagnosis, while nephrotic syndrome accounted for 28% and Henoch-Sch?nlein purpura nephritis accounted for 16% of renal disease. Mortality in children with renal disease was 0.4% (two of 505). All children with acute glomerulonephritis recovered or improved at last follow-up, regardless of the relationship to a streptococcal infection. In children with uncomplicated nephrotic syndrome, 91% had a complete or partial response to corticosteroids. Nephritis developed in 81 of 278 patients with Henoch-Sch?nlein purpura (29%). Since 1956, a dramatic decrease in the diagnosis of acute glomerulonephritis has occurred at this pediatric hospital. Nephrotic syndrome, in contrast, has increased from 45.3 cases per year in the 1956-to-1965 decade to 146 cases annually in the period from 1986 to 1992. Similarly, Henoch-Sch?nlein purpura has increased from 45.3 cases annually in the 1956-to-1965 period to 238 cases per year in the past 6 years. The incidence of nephritis in patients with Henoch-Sch?nlein purpura has remained constant at 29% in the past 36 years. These data should be helpful for individuals nephrologists in China.

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DOI 10.3760/cma.j.issn.1001-7097.1996.01.110
发布时间 2022-08-29(万方平台首次上网日期,不代表论文的发表时间)
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中华肾脏病杂志

中华肾脏病杂志

1996年12卷1期

28-31页

ISTICPKUCSCDCA

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