摘要目的:探讨云南省安宁市60岁及以上人群糖尿病患病情况及其影响因素。方法:本研究为横断面研究。于2019年9月至2020年1月间，用多阶段分层整群抽样法选取云南省安宁市57个自然村的60岁及以上人群，记录研究对象的年龄、民族、所在地区经济发展水平等，记录其身高、体重并计算体重指数（BMI），检测空腹血糖（FPG）、总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C），计算血脂异常检出率。依据糖代谢状态，将研究对象分为糖尿病组（FPG≥7.0 mmol/L或既往诊断为糖尿病）、空腹血糖受损组（6.1 mmol/L≤FPG<7.0 mmol/L）和血糖正常组（FPG<6.1 mmol/L）。采用方差分析、Kruskal-Wallis H检验、χ2检验或Cochran-Armitage趋势χ2检验进行组间比较，采用多因素logistic回归模型分析法分析糖尿病的影响因素。 结果:共纳入研究对象9 447例。其中，糖尿病组1 630例，空腹血糖受损组1 267例，血糖正常组6 550名。糖尿病患病率为17.25%（1 630/9 447）。汉族人群糖尿病患病率高于少数民族，经济水平较高地区人群患病率高于经济发展中等地区（ P<0.05）。多因素logistic回归分析结果显示，经济发展水平和少数民族对安宁市60岁及以上糖尿病患病率有跨层交互作用（OR=0.307，95%CI 0.190~0.494， P<0.001），血脂异常（OR=1.822，95%CI 1.612~4.687， P=0.042）、超重（OR=2.749，95%CI 1.099~3.023， P=0.004）、年龄（OR=1.562，95%CI 0.705~1.977， P=0.032）均是糖尿病的危险因素。 结论:云南省安宁市60岁及以上人群糖尿病患病率为17.25%。经济发展水平和少数民族对老年人糖尿病患病率有跨层交互作用，血脂异常、超重和年龄是糖尿病发病的主要危险因素。

abstractsObjective:To investigate the prevalence and influencing factors of diabetes in people (≥60 years old) in Anning City, Yunnan Province.Methods:This was a cross-sectional study (from September 2019 to January 2020) using multi-stage stratified group sampling with 9 447 people (≥60 years old) from 57 villages in Anning City. The data of individual′s information were recorded, such as age, nation, local economic development level, height, weight, body mass index (BMI), fasting plasma glucose (FPG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol(LDL-C), then the detection rate of the dyslipidemia was calculated. All participants were divided into diabetic group (FPG≥7.0 mmol/L or previously diagnosed diabetes), impaired fasting glucose group (6.1 mmol/L≤FPG<7.0 mmol/L), and normal glucose group (FPG<6.1 mmol/L) based on their glucose metabolic status. Analysis of variances, Kruskal-Wallis H test, chi-square test or Cochran-Armitage trend test were used to compare the indicators within the groups, with the multivariate logistic regression model was adopted to analyze the influencing factors of diabetes. Results:A total of 9 447 individuals were included. Among them, 1 630 cases in diabetic group, 1 267 cases in impaired fasting glucose group, and 6 550 cases in normal glucose group. The prevalence of diabetes was 17.25% (1 630/9 447). The prevalence of diabetes in the Han nationality was significantly higher than that in the minorities, and the rate in high economic level area was significantly higher than that in middle economic level area ( P<0.05). Multi-level logistic regression analysis suggested that there was a cross interaction between the different levels of economic development, and ethnic minorities on the prevalence of diabetes in the elderly(≥60 years old, OR=0.307,95%CI 0.190-0.494, P<0.001), dyslipidemia (OR=1.822, 95%CI 1.612-4.687, P=0.042), overweight (OR=2.749, 95%CI 1.099-3.023, P=0.004), age (OR=1.562, 95%CI 0.705-1.977, P=0.032) were all risk factors for diabetes. Conclusions:The prevalence of diabetes in people aged 60 years and above in Anning city of Yunnan is 17.25%. Moreover, the level of economic development and ethnic minorities have cross-layer interaction on the prevalence of diabetes in people aged 60 years old and above. The main risk factors for diabetes include dyslipidemia, overweight and age.