摘要羊水栓塞是一种致死性的产时并发症,有2种表现类型.典型的羊水栓塞表现为呼吸循环衰竭,随后出现弥散性血管内凝血;非典型羊水栓塞仅表现为不能解释的弥散性血管内凝血,此型存活率较高.羊水栓塞的病生理机制为类过敏炎症反应.临床用药选择上,米力农能降低肺动脉压力,同时有正性肌力、降低心率的作用,可改善右心室功能,是目前治疗羊水栓塞引发的呼吸循环衰竭的首选药物.对羊水栓塞的抢救需多学科团队合作进行,熟练掌握重症医学知识和技能的麻醉科医师常在抢救中起到举足轻重的作用.

abstractsAmniotic fluid embolism(AFE) is a fatal intrapartum complication. Typical AFE is characterized by respiratory and circulatory failure, followed by disseminated intravascular coagulation(DIC), while atypical AFE, which had a higher survival possibility, presents with unexplained DIC only. Recent findings support an anaphylactoid inflammatory mechanism underlying the pathophysiology of AFE. Milrinone is currently the first choice for AFE due to its several functions, such as reducing pulmonary artery pressure, and improving right ventricular function through lowering heart rate and positive inotropic action. A multidisciplinary team is required in the rescue of AFE and medical staff who are skilled in critical medicine (such as anesthesiologists) often play a pivotal role.