摘要本文对产前糖皮质激素（antenatal corticosteroid, ACS）应用于有早产风险的不同孕妇群体的有效性及安全性进行综述。主要内容如下：（1）胎儿生长受限：更易出现新生儿低出生体重，不推荐无指征地重复疗程应用；（2）合并绒毛膜羊膜炎的未足月胎膜早破：虽有益，但急性绒毛膜羊膜炎者宜尽快分娩，不推荐因应用ACS而推迟分娩；（3）双胎/多胎妊娠：推荐与单胎同剂量、同疗程应用，有效性是否相同尚存争议。

abstractsWe review the safety and efficacy of antenatal corticosteroid (ACS) in different pregnant populations at risk of preterm birth. According to the current evidence, attention should be paid to the following aspects: Pregnant women with fetal growth restriction exposuring to ACS are more likely to deliver a low birth weight infant, repeated administration without indications is not recommended; Though ACS is beneficial to pregnant women with premature rupture of membranes complicated by chorionic amniotic inflammation, it is not recommended to use uterine inhibitors for completing the treatment of ACS. For those with acute chorionic amniotic inflammation, pregnancy should be terminated as soon as possible; For twin/multiple pregnancies, the ACS therapy is the same as for singletons, but the efficacy is controversial.