摘要目的 研究数字医学技术在肝癌外科治疗中的临床应用价值.方法 收集2008年2月至7月南方医科大学珠江医院肝胆外科收治的11例原发性肝癌患者的64排螺旋CT扫描数据,其中肝细胞癌9例,胆管细胞癌2例.将收集的数据输入自主研发的医学图像处理系统进行程序分割、三维重建,然后把重建的三维模璎导入到FreeForm Modeling System进行平滑,利用系统的力反馈没备进行肝癌的手术治疗及肝动脉化疗泵放置的仿真研究.以三维苇建模型及仿真手术的结果用于术前指导手术方式的选择并与术中结果相比较.结果 11例患者重建的肝脏、肝动脉、门静脉、肿瘤模型相巨空间结构清晰,可轻松地观察剑肿瘤的血供类型,计算出肿瘤占肝脏的体积百分比;在建立的仿真环境中,使用PHANTOM操纵"仿真器械"及"仿真化疗泵"仿真肝切除术及肝动脉置泵的过程,整个过程有力的感受,与临床手术过程相符,可实时指导临床手术.结论 数宁医学有助于充分了解肝脏血管变异情况及肝脏管道与肝癌的空间结构关系,有助于肝癌切除的彻底性,又可最大限度地保留正常肝组织,减少术中出血,降低手术风险及并发症.

abstractsObjective To study the clinical application of digital medical in the operation on primary liver cancer. Methods The patients (n=11) with primary hepatic carcinoma treated between February and July 2008, including 9 cases of hepatocellular carcinoma, 2 cases of cholangiocellular carcinoma,were scanned using 64 slices helicon computerized tomography (CT) and the datasets was collected. Segment and three-dimensional (3D) reconstruction of the CT image was carried out by the medical image processing system which was developed. And the 3D moulds were imported to the FreeForm Modeling System for smoothing. Then the hepatectomy in treatment of hepatoma and implanting of catheter were simulated with the force-feedback equipment (PHANToM). Finally,3D models and results of simulation surgery were used for choosing mode of operation and comparing with the findings during the operation. Results The reconstructed models were true to life, and their spatial disposition and correlationship were shown clearly; Blood supply of primary liver cancer could be seen easily. In the simulation surgery system, the process of virtual partial hepatectomy and implanting of catheter using simulation scalpel and catheter on 3D moulds with PHANTOM was consistent with the clinical course of surgery. Life-like could be felt and power feeling can be touched during simulation operation. Conclusions Digital medical benefited knowing the relationship between primary liver cancer and the intrahepatic pipe. It gave an advantage to complete primary liver cancer resection with more liver volume remained. It can improve the surgical effect and decrease the surgical risk and reduce the complication through demonstrating visualized operation before surgery.