摘要目的 研究一种与捆绑式胰肠吻合术和捆绑式胰胃吻合术互补的术式--捆绑式胰管对黏膜吻合术的可行性.方法 (1)动物实验:对6只成年新西兰兔行胃肠造瘘术,两个造瘘口分别用导尿管、硅胶管、输液器管作为支撑管连接,导管两端分别置入胃腔与肠腔内,造瘘口荷包缝合,胃壁与肠壁浆膜层拉拢缝合周定.观察胃肠造瘘口处渗漏及愈合情况,显微镜下观察胃黏膜与空肠黏膜愈合情况.(2)临床实践:对7例患者施行捆绑式胰管对黏膜吻合术.手术方法包括:胰端的准备、肠侧的准备、胰断端与空肠对合固定的准备、吻合的实施、最后施行胰断端与空肠的对合固定.术后定期检测腹腔内引流管和血淀粉酶以及各种并发症的情况.胰漏按来源不同分为胰腺实质漏(胰创面漏)和吻合口漏两种.结果 动物实验结果显示愈合良好.临床全部病例均未出现吻合口漏,但有2例腹腔内引流液淀粉酶出现一过性增高,引流量均未超过50 ml/d,未影响患者康复,属于胰腺实质漏(胰腺创面漏).结论 捆绑式胰管对黏膜吻合术是一种简单安全的吻合方法,给外科医生提供了一种新的选择,以便在面对不同的患者时,能够灵活采用不同的方法去取得最理想的治疗效果.

abstractsObjective To study the feasibility of binding pancreatic duct to mucosa anastomosis (BDM)-a complementary procedure to both binding pancreaticojejunostomy and binding pancreaticogastrostomy. Methods (1) Animal experimental study: gastrostomy and jejunostomy were performed on six adult New Zealand rabbits. The gastrostomy and jejunostomy shared a same stent (rubber urethral catheter, silicone tube or plastic infusion tube). Both ends of the stent were placed in gastric and enteric cavity. Purse-string suture was performed around the stent before the jejunum and the stomach were brought together for fixation by few stitches. And to observe whether the purse-string suture around a plastic tube,rubber tube or silicon tube inserted into jejunum and/or stomach can prevent leaking out of the jejunal or gastric content to cause peritonitis. (2)Clinically 7 patients were performed with BDM anastomosis. The procedure was consisted of five steps: preparation of the pancreatic stump; preparation of the jejunum;preparation of the fixing sutures between the pancreatic stump and the jejunum; implementation of the anastomosis; lastly, fixation of the jejunum beside the pancreas stump. Post-operative periodic examination of the blood amylase and the amylase in the abdominal drainage. Pancreatic fistula was classified in to two categories: parenchymal fistula (pancreatic cut surface fistula) and anastomotic leakage. Results Animal experiment did not show any leakage around the plastic tube or silicon tube inserted into jejunum and(or) stomach. There was no anastomotic leak in all the patients. There was transient increase of amylase in two cases, but the volume of drainage did not exceed 50 ml/d and the recovery of the patients was not affected.Conclusions BDM is a simple, safe and easy procedure to perform. It provides to the surgeons with a new option in different situations to achieve the most ideal surgical result.