摘要随着供肺短缺矛盾的日益突出和现代肺保存和修复技术的发展，越来越多的边缘供肺被再评估或修复后应用于临床。为了评估修复供肺、改善供肺功能，体外肺灌注（ EVLP ）应运而生并逐渐发展成熟。目前，对于EVLP的适应证、EVLP转流后供肺质量可及不可进行肺移植的标准，学界已基本达成共识。临床常用的EVLP主要有Toronto技术、Lund技术和Hannover?Madrid技术3种，其主要区别在于左心房是否处于开放状态、灌注液是否含有红细胞及目标灌注流量的大小。在世界上多个肺移植中心，EVLP的临床应用均已积累了相当多的经验，同时学者们也在谋求EVLP技术细节的改进，尝试在管路中加入药物、改变机械通气使用气体、在动物模型中转染腺病毒基因等，但目前还处于实验研究阶段。最近出现的便携式EVLP装置，突破了传统肺移植供肺保存中静态冷保存的限制，可在转移过程中在常温下对供肺进行保存、评估、修复，从而增加了供肺的保存时间和取肺半径，也提高了供肺的利用率。

abstractsThe shortage of donor lung remains one of the major problem for lung transplantation?With the development of modern lung preservation and repair technique, increasing marginal lung donors have been re?assessed and finally utilized for transplantation? The ex vivo lung perfusion technique ( EVLP ) was designed and has been developed for evaluation and repair of the lung? Nowadays, the indication of EVLP and the standard of qualified donor lung have reached a consensus according to the foreign publications? The EVLP system could be classified into three categories: the Toronto technique, the Lund technique and Hannover?Madrid technique? The major differences between the Toronto technique and the other two technique are the open left atrium status, the use of Steen solution mixed with erythrocyte and the perfusion at flows correspondent to 100% of the donor predicted cardiac output? With the accumulating experience, researchers have tried to imply some drugs in the circulation, modify the ventilation gas and delivery of adenoviral vector gene in order to improve the lung quality? But these are still in the research phase? Recently, the portable EVLP device has been developed and the lung preservation, assessment and repair could be conducted during transportation? So it could prolong the preservation time and expand the transportation distance of donor lung.