摘要目的:探讨三维打印技术辅助下预开窗或分支支架腔内修复术（F/B-TEVAR）治疗A型夹层开放术后吻合口漏的临床效果。方法:本研究为多中心回顾性病例系列研究。回顾性分析2019年1月至2023年12月我国12家医疗中心收治的Stanford A型夹层开放术后吻合口漏的16例患者资料。手术均由南京市鼓楼医院血管外科团队主导完成。男性12例，女性4例，年龄（58.1±8.2）岁（范围：42~75岁）。根据患者术前主动脉CT血管造影检查数据制作三维打印模型或三维参数曲面平面拓扑导板，术中辅助体外定位预开窗位置，并结合支架束径、内分支技术完成腔内修复术。观察手术情况和并发症情况，并通过CT检查评估临床效果。结果:所有患者的手术均顺利完成，无中转开放手术。1例患者初次开放修复术放置的远端支架移位，术中遮盖主体支架窗口，中转原位开窗手术治疗。手术时间（332.6±111.2）min（范围：80~460 min），术后无肾功能不全和截瘫发生，无分支动脉丢失。随访时间［ M（IQR）］为18（18）个月（范围：6~36个月），术后6个月随访率为16/16、12个月为10/16、24个月为8/16、36个月为2/16。随访期间发生内漏3例，脑梗死1例，死亡1例，其余患者的支架均在位良好，分支通畅。 结论:三维技术引导下F/B-TEVAR治疗A型夹层开放术后吻合口漏的中短期效果良好。

abstractsObjective:To evaluate the clinical value of three-dimensional(3D) printing-assisted fenestrated/branched endovascular aortic repair (F/B-TEVAR) for the treatment of endoleak after open surgery for type A aortic dissection.Methods:A multi-center retrospective case series analysis was conducted on 16 patients with anastomotic leakage following Stanford type A aortic dissection open repair, admitted to 12 medical centers between January 2019 and December 2023. All surgeries were led by the vascular surgery team from Department of Vascular Surgery, Nanjing Drum Tower Hospital. The study included 12 males and 4 females, with an age of (58.1±8.2) years (range: 42 to 75 years). Preoperative patient-specific 3D-printed models or 3D parametric surface topological guides were created based on aortic CT angiography data. These models assisted intraoperative external positioning of fenestration sites, combined with stent diameter selection and inner branch techniques to complete endovascular repair. Surgical procedures, complications, and clinical outcomes were evaluated, with follow-up CT imaging to assess efficacy.Results:All patients successfully underwent surgery without conversion to open repair. One patient had distal stent migration from a prior open repair, requiring intraoperative coverage of the main stent window and conversion to an in situ fenestration procedure. The mean operative time was (332.6±111.2)minutes (range: 80 to 460 minutes). No renal failure, paraplegia, or branch artery loss occurred. Postoperative follow-up ( M(IQR)) was 18(18) months(range: 6 to 36 months), with follow-up rates of 16/16 at 6 months, 10/16 at 12 months, 8/16 at 24 months, and 2/16 at 36 months. During follow-up, endoleak occurred in 3 patients, cerebral infarction in 1 patient, and death in 1 patient. The remaining patients demonstrated stable stent positioning, patent branches, and no endoleak. Conclusion:3D technology-guided F/B-TEVAR shows favorable mid-to short-term outcomes in treating anastomotic leakage after open repair of type A aortic dissection.