摘要目的 观察Tomatis音频转换听觉训练对乳腺癌化疗患者执行功能障碍的影响.方法 纳入符合条件的乳腺癌化疗且存在执行功能障碍的患者80例,按随机数字表法分成对照组和实验组,每组40例.实验组采用Tomatis高低音频转换听觉训练,对照组采用未经处理的普通音乐训练,每个阶段连续干预5d间隔21 d,2组患者各干预4个阶段,分别于干预前和干预4个阶段后(干预后),采用执行缺陷综合征的行为评价测验工具(BADS)对2组患者的执行功能(包括规则转换能力、问题解决能力、计划能力、监督行为、组织能力等)进行测评.结果 干预后,实验组的规则转换卡片测验(RSCT)、动作计划测验(APT)、找钥匙测验(KST)、修订六元素测验(MSET)评分及BADS总分分别为(3.03±0.62)、(2.60±0.63)、(2.08±0.62)、(2.88±0.52)和(13.88±1.77)分,5项评分均较干预前[(2.35±0.77)、(1.68±0.86)、(1.38±0.84)、(2.35±0.62)和(11.00±2.55)分]明显提高(P＜ 0.05);而对照组干预后仅在KST评分[(1.83±0.78)分]和BADS总分[(11.68±1.19)分]两项评分明显高于干预前[(1.40±0.78)和(10.98±1.39)分],差异有统计学意义(P＜0.05);且干预后实验组的RSCT、APT、MSET评分和BADS总分均明显高于对照组干预后[(3.03±0.62)vs(2.48±0.64)、(2.60±0.63) vs (1.58±0.64)、(2.88±0.52) vs (2.58±0.59)、(13.88±1.77)vs(11.68±1.19)分],组间差异有统计学意义(P＜0.05).结论 Tomatis音频转换听觉训练可改善乳腺癌化疗患者的执行功能障碍,且效果优于普通音乐训练方法.

abstractsObjective To observe the effect of Tomatis converted auditory training on the executive functioning of breast cancer patients undergoing chemotherapy.Methods Eighty breast cancer patients with the executive dysfunction who were undergoing chemotherapy were divided into a control group and an experimental group,each of 40.The experimental group was given Tomatis high and low frequency auditory training,while the control group was given ordinary music training.The patients in both groups were treated in 4 stages,each of 5 consecutive days with intervals of 21 days.The Chinese Version of the Behavioral Assessment of Dysexecutive Syndrome (BADS) was used to evaluate both groups before and after the intervention,including rule transformation ability,problem solving ability,planning ability,supervising ability and organizing ability.Results After the intervention,the experimental group had a significantly higher average score than before the intervention in the rule-switching card test,the action planning test,the key-finding test,and the modified six-element test.Their average BADS score was also significantly improved.The control group showed a significantly better average score only in the key-finding test and in its average BADS total score.After the intervention,the experimental group had a significantly higher average score than the control group in the rule-switching card test and the action planning and six-element tests.Its average BADS rating was also significantly better.Conclusion Tomatis high and low frequency auditory training can improve the executive function of patients undergoing chemotherapy for breast cancer.Its effect is better than that of ordinary music training.