摘要对NIH小鼠的IgE，IgG和IgG1水平与3-MCA诱发肿瘤发生发展关系的初步研究结果显示：IgE，IgG或IgG1水平高低对肿瘤的诱发率无影响。但高IgE状态可延长小鼠存活时间（P<0.05），对带瘤小鼠存活时间的延长具有非常显著意义（P<0.01），IgG或IgG1水平升高对小鼠存活时间和带瘤小鼠存活时间的延长不具有统计学显著意义。本实验结果亦未提示IgE，IgG或IgG1对肿瘤大小和肿瘤生长率的影响具有统计学显著意义。

abstractsThe relationship between murine IgE, IgG and IgG1 level and fibrosarcoma induced by 3-Methylcholanthrene in NIH mice was studied. The results showed: IgE, IgG or IgGl had no significant effect on tumor incidence; The high IgE level could extend the survival time of 3-Methylcholanthrene injected mice (p<0.05) and survival time of tumor bearing mice (P<0.01) , while IgG or IgG1 could not. The data from this study did not show that IgE, IgG or IgG1 had any significant effect on the tumor size and the tumor growth rate. The probable mechanism involved was discussed.