摘要目前戊型肝炎病毒(HEV)感染的实验室诊断方法是检测HEV抗体(HEV IgM/IgG)或HEV核酸(HEV RNA)。近年来,基于对HEV病毒体蛋白结构及免疫性的研究,发展了HEV抗原(HEV Ag)检测方法。本文就HEV Ag检测方法的建立、HEV Ag检测的意义及在HEV感染诊断中的应用进行综述。
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abstractsCurrently, hepatitis E virus (HEV) infection is diagnosed mainly by the detection of HEV-specific IgM/IgG or HEV RNA. In recent years, the method for detecting HEV antigen (HEV-Ag) has been developed based on the study of the structure and immunity of HEV virion protein. This article reviewed the development of ELISA for HEV-Ag detection and the significance and application of HEV-Ag detection in the diagnosis of HEV infection.
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