摘要目的 探讨内镜下胃肠道黏膜黄斑辅助诊断血吸虫病的特异性和临床价值.方法 对8000例胃镜、结肠镜受检者行常规内镜检查,观察胃肠道血吸虫性黏膜变化,并随机活检,将胃镜、结肠镜检查结果进行统计学分析,总结胃肠道黏膜黄斑的发现率.结果有702例内镜下发现消化道黏膜血吸虫性改变,发现率为8.8%(702/8000).胃镜受检者中,516例发现血吸虫病,发现率为8.0%(516/6421);发现6例患者存在黏膜黄斑,发现率为0.1%(6/6421),占胃型血吸虫病者总数的1.2%(6/516).结肠镜受检者中,186例发现血吸虫病,发现率为11.8%(186/1579);发现177例患者存在黏膜黄斑,发现率为11.2%(177/1579),占大肠型血吸虫病者总数的95.2%(177/186).结论 内镜下发现胃肠道黏膜黄斑并进行适当的活检,可辅助对血吸虫病的诊断,具有一定的临床应用价值,为为临床诊断血吸虫病开辟了一条新的途径.

abstractsObjective To evaluate the specificity and clinical value of endoscopy detected gastroin-testinal mucosa macula in diagnosis of schistosomiasis. Methods The findings of routine gastroscopy and colonoscopy performed in 8,000 subjects, including characteristic mucosal changes of schistosomiasis, detec-tion of macula and results of biopsy, were retrospectively analyzed. Results Mucosal changes caused by schistosomiasis were detected in 702 cases (8.8%). Among 6,421 cases of gastroscopy, 516 (8.0%) were diagnosed as schistosomiasis, with mucous macula found in 6 (0.1%, 6/6421), which accounted for 1.2% (6/516) of gastric schistosomiasis. Of the 1,579 cases of colonoscopy, 186 (11.8%) were diagnosed as schistosomiasis, with mucous macula detected in 177 (11.2%, 177/1579), which accounted for 95.2% (177/186) of colonic schistosomiasis. Conclusion Detection of mucous macula through gastroscopy and colonoscopy, accompanied with biopsy, plays an important role in diagnosis of schistosomiasis.