摘要目的 探讨单气囊小肠镜(SBE)、双气囊小肠镜(DBE)检查与胰腺炎、高淀粉酶血症并发症的相关性.方法 连续收集2011年9月至2012年12月间56例行SBE和DBE检查患者的临床资料,按气囊辅助式小肠镜类型及进镜途径进行分组(即分成SBE经口组、SBE经肛组、DBE经口组和DBE经肛组)并整理数据,统计分析气囊辅助式小肠镜类型及进镜途径对镜检相关胰腺炎、高淀粉酶血症并发症发生率的影响.结果 SBE经口组19例,发生镜检相关高淀粉酶血症12例(63.16％)、胰腺炎1例;SBE经肛组12例,发生镜检相关高淀粉酶血症2例(16.67％),无镜检相关胰腺炎发生;DBE经口组15例,发生镜检相关高淀粉酶血症11例(73.33％),无镜检相关胰腺炎发生;DBE经肛组10例,无镜检相关高淀粉酶血症、胰腺炎发生.术后高淀粉酶血症发生率,SBE经口组与SBE经肛组比较(P=0.009)、DBE经口组与DBE经肛组比较(P =0.001)差异均有统计学意义,而SBE经口组与DBE经口组比较(P=0.415)、SBE经肛组与DBE经肛组比较(P=0.558)差异无统计学意义.结论 气囊辅助式小肠镜检查术后较易并发高淀粉酶血症,经口途径较经肛途径更易并发,而是否易发与气囊辅助式小肠镜类型无关;至于气囊辅助式小肠镜检查与术后胰腺炎的相关性,由于样本量太少,未能得出有价值的临床结论.

abstractsObjective To study the correlation between the two procedures of single-balloon and double-balloon enteroscopy and the complications of pancreatitis and hyperamylasemia.Methods Data of 56 patients who received double-balloon or single-balloon enteroscopy in our center were consecutively enrolled in the prospective study from September 2011 to December 2012.They were assigned to different groups according to the endoscope type and access route,i.e.,SBE peroral group,SBE peranal group,DBE peroral group,and DBE peranal group.And correlation of endoscope type and access route with complications was analysed.Results Of the 19 cases of SBE peroral group,endoscopy related hyperamylasemia occurred in 12 cases(63.16％)and acute pancreatitis in 1.These two variables were 2 (16.67％)and none in SBE peranal group (n =12).In DBE peroral group (n =15),the variables were 11 (73.33％)and none,while those in the DBE peranal group (n =10)were both 0.There were significant differences between single balloon peroral group and peranal group (P =0.009),and between double-balloon peroral and peranal group (P =0.001).There were no significant differences between single balloon peroral group and double-balloon peroral group (P =0.415) or between single balloon peranal group and double-balloon peranal group (P =0.558).Conclusion There are high risks of hyperamylasemia after enteroscopic examination.The incidence of hyperamylasemia in peroral group is significantly higher than that in peranal group.It has no correlation with the endoscopic type.A large scale study is still needed for a more clinically valuable conclusion.