摘要目的 评价自体皮片移植术预防食管环周早癌内镜黏膜下隧道剥离术(ESTD)后食管狭窄的安全性和有效性.方法 2018年1月至2018年3月,5例食管环周早癌患者于解放军总医院接受ESTD联合自体皮片移植术.术后通过内镜随访,观察皮片生长情况,有无食管狭窄及并发症发生情况.结果 5例患者均成功实施了ESTD和自体皮片移植术.无食管穿孔、出血、创面感染和支架移位等并发症发生.平均移植皮片成活率为86.0％.4例患者术后平均随访9.5个月,未发生食管狭窄;1例患者术后发生食管狭窄并进行了球囊扩张,术后随访8个月内未再发生狭窄.结论 自体皮片移植术可能是预防食管环周早癌ESTD术后食管狭窄的一种安全且有效的方法.

abstractsObjective To assess the efficacy and safety of autologous skin-grafting surgery ( ASGS) in the prevention of esophageal stenosis after complete circular endoscopic submucosal tunnel dissection ( ESTD) for early esophageal cancer. Methods Between January 2018 and March 2018, five patients with early esophageal cancer underwent complete circular ESTD and ASGS in Chinese PLA General Hospital. The skin-graft survival situation, and occurrence of esophageal stenosis and complications were observed by endoscopy follow-up. Results Complete circular ESTD and ASGS were successfully performed in all 5 patients, and no complications including perforation, bleeding, wound infection or stent migration occurred. The mean skin-graft survival rate was 86. 0％. Four patients did not experience esophageal stenosis over the mean follow-up of 9. 5 months. One patient experienced esophageal stenosis after operation, and underwent endoscopic balloon dilatation. No stenosis occurred in 8 months of follow-up. Conclusion ASGS is a safe and effective method to prevent esophageal stenosis after complete circular ESTD.