摘要目的:评估SpyGlass内镜直视系统(以下简称SpyGlass)对不明原因胆道狭窄的诊断价值。方法:收集2012年9月至2017年8月期间因不明原因胆道狭窄在杭州市第一人民医院行SpyGlass检查的患者资料，统计分析SpyGlass诊断不明原因胆道狭窄的准确性。结果:共有88例不明原因胆道狭窄患者接受了SpyGlass检查，操作成功率97.7%(86/88)，SpyGlass视觉诊断不明原因胆道狭窄良恶性的灵敏度为98.1%(52/53)，特异度为96.9%(31/32)，准确率为97.6%(83/85)，阳性预测值为98.1%(52/53)，阴性预测值为96.9%(31/32)。3例(3.5%, 3/86)患者术后出现相关并发症，均经内科保守治愈。结论:SpyGlass对于不明原因胆道狭窄诊断具有很高的灵敏度和准确率，并发症发生率低，安全有效。

abstractsObjective:To investigate the diagnostic value of SpyGlass endoscopy system (short for SpyGlass) for indeterminate bile duct stricture.Methods:Data of patients who underwent SpyGlass examination for indeterminate bile duct stricture at Hangzhou First People′s Hospital from September 2012 to August 2017 were reviewed. The diagnostic value of SpyGlass for indeterminate bile duct stricture was analyzed.Results:A total of 88 patients with indeterminate biliary stricture were diagnosed with SpyGlass. The procedure success rate was 97.7% (86/88). The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of SpyGlass for indeterminate bile duct stricture were 98.1%(52/53), 96.9% (31/32), 97.6% (83/85), 98.1% (52/53)and 96.9% (31/32), respectively. Three patients (3.5%, 3/86) had postoperative complications and were cured by conservative treatment.Conclusion:SpyGlass is safe and effective for indeterminate biliary stricture with high sensitivity and accuracy and low incidence of complications.