摘要评价内镜超声引导下细针抽吸术（endoscopic ultrasound-guided fine needle aspiration，EUS-FNA）对内镜活检阴性的消化道恶性狭窄的诊断价值及安全性。回顾性分析2016年7月—2020年1月于苏州大学附属第二医院行CT检查提示消化道恶性肿瘤伴管腔完全狭窄、内镜活检阴性行EUS-FNA的患者资料，观察术中及术后并发症，评估技术成功率及EUS-FNA的准确性。共纳入11例患者，男7例、女4例，平均年龄60.3岁；其中食管病灶8例，直肠病灶3例。11例均成功实施了EUS-FNA，其中病理提示恶性肿瘤10例，未见肿瘤细胞1例，所有患者未发生并发症。对内镜活检阴性的消化道恶性狭窄患者实施EUS-FNA是一种安全、有效的诊断方法。

abstractsTo evaluate the diagnostic value and safety of endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in patients with biopsy-negative malignant gastrointestinal stricture, a retrospective analysis was performed on data of patients whose computed tomography scan showed gastrointestinal malignant tumor with complete lumen stricture and endoscopic biopsy results showed negative, who underwent EUS-FNA in the Second Affiliated Hospital of Soochow University from July 2016 to January 2020. Perioperative complications, technical success rate and accuracy of EUS-FNA were analyzed. Eleven cases included in the study, including 7 males and 4 females, with mean age of 60.3 years. There were 8 esophageal strictures and 3 rectal strictures. All patients successfully underwent EUS-FNA, and malignant tumor was found in 10 cases and no tumor cell was found in 1 case. No complications were reported. EUS-FNA is a safe and valuable approach to diagnosing biopsy-negative malignant gastrointestinal strictures.