摘要采用常规胃镜下十二指肠降部粘膜活检，对20例吸收不良综合征十二指肠降部粘膜绒毛病理，及微绒毛超微结构进行观察，并行相应图像作定量分析。结果表明：吸收不良综合征组绒毛高度降低、宽度增加、陷窝深度加深，与对照组比较差异均有非常显著性（P<0.01）；微绒毛密度减低、高度减低、表面积缩小，与对照组相比差异均有非常显著性（P<0.001）。结论：十二指肠降部粘膜活检可用于吸收不良综合征的诊断。

abstractsBiopsies of descending duodenum from 20 patients with malabsorption syndrome were taken through routine gastroscopy. Observations on the pathological changes of mucosal villi and ultrastructural changes of microvilli as well as a quantitative imaging analysis were carried out correspondingly. Our results showed significant shortening and widening of villi and deepening of crypts (P<0.01). Quantitative imaging analysis showed a significant decrease in the density, the height and surface area of the microvilli (P<0.001). Our results confirm that biopsies of descending duodenum can be used in the diagnosis of malabsorption syndrome.