摘要目的 探讨社区居民婚姻状况与外周血管疾病(PAD)之间的关系.方法 2007年5月至8月,通过多阶段分层整群随机抽样方法调查北京市社区居民10 054名.运用广义线性混合模型,以社区站作为群组随机因素,分析不同婚姻状况下不同性别和年龄人群PAD的患病风险.结果 调整PAD危险因素(年龄、地区、血脂、血糖、血压、肥胖、吸烟、饮酒和体育活动)的影响之后,在45岁以下人群中,未婚男性与已婚男性比较PAD患病的OR值为1.56(0.39 ～6.35),未婚女性与已婚女性比较PAD患病的OR值为0.75(0.22 ～2.57)；在45岁及以上人群中,未婚男性与已婚男性比较PAD患病的OR值为1.61 (0.77 ～3.35),未婚女性与已婚女性比较PAD患病的OR值为1.78( 1.23 ～2.58).45岁及以上未婚女性的年龄、腰围、收缩压、空腹血糖、总胆固醇、低密度脂蛋白胆固醇和吸烟比例均高于已婚者(P均＜0.01).结论 45岁及以上女性的婚姻状况与罹患PAD有关.女性雌激素的变化和PAD危险因素的分布可能是造成这种现象的原因.

abstractsObjective To investigate the relationship between marital status and prevalence of peripheral arterial disease (PAD) among Beijing residents.Methods From May to August 2007,10 054 residents were interviewed to collect demographic and biochemistry information.Generalized linear mixed model was used to determine the relationship between marital status and prevalence of PAD in terms of OR and corresponding 95％ confidence intervals.Results After adjusting the traditional risk factors including age,area,lipid,serum glucose,blood pressure,central obesity,smoking,drinking and physical activities for PAD,relationship between marital status and prevalence of PAD was found both at the female and male groups of those with 45 years or older.Compared with married men,OR and 95％ confidence interval of PAD for unmarried men were 1.56 (0.39 - 6.35 ) and 1.61 (0.77 - 3.35 ) for those with 45 years younger and older respectively,while compared with married women,OR and 95％ confidence interval of PAD for unmarried women were 0.75 ( 0.22 - 2.57 ) and 1.78 ( 1.23 - 2.58 ) for those with 45 years younger and older respectively.Significant differences ( all P ＜ 0.01 ) were found between married and unmarried women of 45 years or older in terms of age,waist circumstances,systolic blood pressure,fasting glucose,total cholesterol,low-density lipoprotein and smoking.Conclusions Peripheral arterial disease was related to marital status for women of 45 years or older among Beijing residents.Estrogen level and the distribution of other PAD risk factors might contribute to the observed finding.