70岁以上老年早期肺癌的手术方式及预后
Surgical procedure and prognosis analysis for elderly stage Ⅰ NSCLC patients above 70 years old
摘要目的 探讨70岁以上老年Ⅰ期肺癌患者的手术方式及对预后的影响.方法 回顾性分析2003年1月至2011年1月间71例70岁以上的Ⅰ期非小细胞肺癌患者.男51例、女20例,年龄70 ~84岁,平均74岁.其中肺楔形切除和肺段切除术22例,肺叶切除术49例.随访2~81个月,平均30个月.结果 肺楔形切除、肺段切除术组及肺叶切除术组术后并发症发生率分别为36.4%和46.9%.术后住院天数11.36天和12.24天.3年总生存率85.9%和78.8%;5年总生存率56.4%和56.9%,以上各组比较均差异无统计学意义.分期为影响预后的独立因素.结论 老年Ⅰ期肺癌患者,肺楔形切除或肺段切除术可获得与肺叶切除术相似的预后.
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abstractsObjective The purpose of this study is to evaluate Surgical Procedure and Prognosis for elderly stage 1NSCLC patients above 70 years old.Methods The patients who were stage Ⅰ non-small cell lung cancer from 2003 to 2007were enrolled ( n =71 ).The median age was 74 years ( ranged from 70 to 84 years).The median follow-up of patients was 30months( ranged from 2 to 81 months).Results The percentages of postoperative complications after sublobar resection and lobectomy patients were 36.4% and 46.9%,respectively.The period in hospital were 11.36 days and 12.24 days.The 3 year survival was 85.9% for patients undergoing sublobar resection and 78.8% for lobectomy.The 5 year survival was 56.4% and 56.9% respectively.No significant difference was observed between two types of surgical procedure in the elderly.Staging is the independent factor of prognosis.Conclusion Lobectomy is still the main therapy method for elderly stage Ⅰ NSCLC patients.Especially,for those who can undergo radical resection.But sublobar resection also appears to be a viable surgical treatment for patients with cardiopulmonary physiologic impairment.
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