摘要目的 探讨二尖瓣反流的患儿置入人工成形环的效果.方法 2015年2月至2017年12月,11例术前中重度二尖瓣反流患儿接受人工二尖瓣瓣成形环置入术,男5例,女6例;手术时年龄(8.0±4.5)岁;体质量(26.1±13.9)kg.患儿术后即刻二尖瓣反流程度均明显改善至轻度(P<0.05).结果 1例早期死亡.1例因为早期溶血,改行二尖瓣置换术.其余患儿顺利出院,随访3个月,二尖瓣反流较术后即刻无加重(P>0.05),心功能无恶化(P>0.05),无其他不良事件.结论 人工二尖瓣瓣环置入治疗小儿二尖瓣反流效果明显,瓣环有潜在生长特性,无需终身口服抗凝药,可扩大小儿二尖瓣成形术的手术指征,改善患儿生活质量,治疗效果良好.

abstractsObjective Mitral valve regurgitation often leads to cardiac insufficiency or even heart failure .Methods We tried a mitral valve annuloplasty with a ring to improve the effect of mitral valvuloplasty , 5 males and 6 females; aged(8.0 ± 4.5)years;weight(26.1 ±13.9)kg.From February 2015 to December 2017, 11 children underwent mitral valve annuloplasty with an mitral valve ring in our hospital.Immediately after surgery, the degree of mitral valve regurgitation was significant im-proved from moderate-severe to mild-moderate(P<0.05).Results 1 case of early death, 1 case had a mitral valve replace-ment because of early hemolysis.The rest of the children were discharged smoothly.The follow-up of 3 months of mitral valve regurgitation was not aggravated comparing with that immediately after surgery(P>0.05).There was no worsening of cardiac function at follow-up(P>0.05), and no other adverse events.Therefore, artificial mitral annuloplasty with a ring is effective in treating mitral regurgitation in children .The annulus had potential growth characteristics and did not require lifelong oral an-ticoagulant.Conclusion For some patients with difficulty, this method of mitral valvuloplasty can enlarge the surgical indica-tion and improve the quality of life of children.The treatment effect is good.