摘要目的 利用眼模型研究球面和非球面人工晶状体(IOL)眼模型焦深.方法 计算机数值模拟实验研究.以Liou-Brennan眼模型为基础在ZEMAX光学设计软件中建立IOL眼模型,模拟植入不同球面和非球面IOL离焦调制传递函数(MTF)曲线,分析瞳孔、非球面设计因素对焦深的影响.结果 550 nm单色光下,球面和非球面IOL眼焦深均随瞳孔直径缩小而增加(FY60AD眼模型6 mm瞳孔1.20D,5 mm瞳孔1.35 D,4mm瞳孔1.70 D,3 mm瞳孔2.46 D; YA60BBR眼模型6 mm瞳孔1.24D,5 mm瞳孔1.48 D,4 mm瞳孔1.80 D,3mm瞳孔2.50 D),球面IOL在负离焦一侧MTF曲线较高,瞳孔直径较大时明显.5 mm瞳孔下消球差的非球面IOL眼在良好聚焦条件下MTF高于球面IOL眼,但焦深小于球面IOL眼(Tecnis Z9000为1.31 D,FY60AD为1.35 D,CeeOn911为1.55 D,YA60BBR为1.48 D),零球差IOL眼焦深降低程度较小(LI61AO为1.42 D).结论 小瞳孔下IOL眼焦深较大,大瞳孔时良好聚焦的非球面IOL眼图像质量高于球面IOL眼,但损失部分焦深,对离焦的耐受能力下降,负离焦时明显.

abstractsObjective To investigate depth of focus (DOF) in spherical and aspheric IOL eye models.Methods Computer numerical simulation experiment was used.IOL eye model based on LiouBrennan eye model was constructed by using ZEMAX optical design software.Different IOL were implanted in this eye model Monochromatic through focus modulation transfer function (MTF) curves were computed.Pupil and aspheric designs＇ effect on DOF were analyzed.Results DOF of eye model increased with pupil shrinkage in 550 nm monochromatic light ( FY60AD 1.20 D at 6 mm pupil,1.35 D at 5 mm pupil,1.70 D at 4 mm pupil,2.46 D at 3 mm pupil; YA60BBR 1.24 D at 6 mm pupil,1.48 D at 5 mm pupil,1.80 D at 4 mm pupil,2.50 D at 3 mm pupil).MTF in spherical IOL eye model was higher with minus defocus,this trend was obvious at larger pupil MTF of aspheric IOL eyes were higher than spherical IOL eyes when well focused at 5 mm pupil,while the DOF was lower in aspheric IOL with negative spherical aberration (Tecnis Z9000 1.31 D,FY60AD 1.35 D,CeeOn911 1.55 D,YA60BBR 1.48 D).DOF decreased less in aspheric IOL with zero spherical aberration ( LI61AO 1.42 D).Conclusions DOF in IOL eye model was higher at smaller pupil. When the pupil was large,well focused aspheric IOL improved optical quality compared with spherical IOL,while DOF and the tolerance to defocus in aspheric IOL were partially lost;this phenomenon was obvious with minus defocus.